The Citizens start the weekend top of the tree and will be eager to carry on their splendid form when they host the struggling Saints
Manchester City will be hoping to return to the top of the Premier League table when they take on Southampton at the Etihad Stadium on Sunday, kick-off 3pm.
Pep Guardiola’s men are behind Liverpool by one point and come up against a Saints side who have failed to score in their last five league games.
Defeat could see Southampton in the bottom three depending on other results, however, the south coast side have kept clean sheets in their last two games so could prove a tough nut to crack.
And City will have to make do without Kevin De Bruyne for up to six weeks, after he sustained ligament damage during their Carabao Cup win over Fulham on Thursday.
Pep Guardiola (Manchester City): “This kind of injury [to De Bruyne] is unlucky. He’s so strong and he’s recovered so well. It was more dangerous than this one.
“We are a stronger team with Kevin than without him, but we have to live without him.”
Mark Hughes (Southampton): “There are always elements of any team that you can look to exploit, no matter how good they are.
“They get into winning positions very quickly which we can’t let happen.”
Manchester City: Ederson, Walker, Stones, Laporte, Mendy, Fernandinho, Silva (C), Sane, Sterling, Bernardo, Aguero
Southampton: McCarthy, Soares, Stephens, Hoedt, Bertrand, Redmond, Ward-Prowse, Lemina, Hojbjerg, Long, Ings